ccnd1 antibody (Boster Bio)
Structured Review

Ccnd1 Antibody, supplied by Boster Bio, used in various techniques. Bioz Stars score: 94/100, based on 31 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/ccnd1/Anti-CCND1+Antibody/pmc13085978-36-0-3
Average 94 stars, based on 31 article reviews
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1) Product Images from "Astragaloside IV targets TUBB4B to inhibit proliferation and promote apoptosis of pituitary tumor cells via the STMN1/ERK pathway"
Article Title: Astragaloside IV targets TUBB4B to inhibit proliferation and promote apoptosis of pituitary tumor cells via the STMN1/ERK pathway
Journal: International Journal of Molecular Medicine
doi: 10.3892/ijmm.2026.5822
Figure Legend Snippet: OE-TUBB4B upregulates STMN1 and activates the ERK pathway. (A) Effect of TUBB4B on GH3 cell cycle progression. (B) Cell cycle distribution. (C) Reverse transcription-quantitative PCR was used to assess the effects of OE-TUBB4B. (D) Transcriptomic sequencing showing Kyoto Encyclopedia of Genes and Genomes pathway enrichment of differentially expressed genes. (E) Transcriptomic sequencing showing the protein-protein interaction network of proteins that interact with TUBB4B (red box indicates key pathway proteins that interact with TUBB4B). (F) Interaction diagram between the TUBB4B and STMN1 proteins from STRING. (G) Cell Counting Kit-8 assay was used to assess the viability of GH3 cells treated with U0126. In GH3 cell lines treated with U0126, the protein expression levels of (H) STMN1, (I) p-STMN1 (I), and cPLA2 (J) were assessed by western blotting (K), and levels of p-cPLA2 (L), ERK (M), p-ERK (N), CCND1 (O), JNK (P), and p-JNK (Q) were also assessed. **** P<0.0001, *** P<0.001, ** P<0.01, * P<0.05 vs. vector. OE, overexpression; TUBB4B, tubulin beta 4B class IVb; STMN1, stathmin 1; p-, phosphorylated; cPLA2, cytosolic phospholipase A2; CCND1, cyclin D1; KD, knockdown; OD, optical density; ns, not significant.
Techniques Used: Reverse Transcription, Real-time Polymerase Chain Reaction, Sequencing, Cell Counting, Expressing, Western Blot, Plasmid Preparation, Over Expression, Knockdown
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